Science

Key Nutrients

Years of research have demonstrated that The Paleo Diet is the most effective diet at satisfying the genetically determined nutritional requirements of humans. This is the key to optimal health.

Explore Key Nutrients Pages

Protein

Protein is one of three macronutrients, along with carbohydrates and fats. While the latter two are our primary sources of energy, proteins serve as the building blocks and signaling molecules of our bodies. While most people understand trans-fats are different from omega-3 fats and complex carbs are healthier than simple carbs, too often they assume all proteins are nutritionally the same.

Carbohydrates

Carbohydrates, one of three macronutrients, are our primary source of rapid energy. All digestible carbs are made from three simple sugars—glucose, fructose, and galactose. Complex carbohydrates, found in vegetables and fruit, are long strings of sugars that break down slowly. Simple carbohydrates are made of just one or a few sugars and can have a dramatic impact on our blood sugar, insulin, and metabolic health if over-consumed.

Fat

The technical term for fat is acylglycerol. The name indicates the chemical structure: one or many fatty acids (acyl groups) are linked to an alcohol (glycerol) via an ester bond. Acylglycerols can have one fatty acid (monoglycerides), two fatty acids (diglycerides), or three fatty acids (triglycerides.) Fat is our long-term source of energy and serves as our primary energy storage.

Fiber

Unlike fats, proteins, and carbohydrates—which our bodies break down and absorb—fiber is not digested by gastrointestinal enzymes. Also known as roughage, fiber is the sum of the constituents of plant foods that are not digested. It has two main components: soluble fiber, which dissolves in water, and insoluble fiber, which does not.

Calcium

Calcium is an essential nutrient and the most abundant mineral in our bodies. Most calcium is found in our bones, but it also serves a critical function in muscle and nerve function. On the Paleo Diet, calcium is the only essential nutrient whose recommended daily allowance is not met. Interestingly, there are proven health consequences of calcium overconsumption, and that has been linked to the rapid rise in heart disease in women.

Iron

Iron is an essential mineral that cannot be synthesized by the body. It is necessary for the transport of oxygen and energy formation. Although the human body can recycle and reutilize this mineral, we lose a small amount of iron daily, which then needs replacing. Good sources of iron include meat, poultry, eggs, and vegetables, though animal sources are more readily absorbed.

Magnesium

Magnesium is the fourth most abundant electrolyte in our bodies. It is critical to both muscle function and acts as a cofactor to over 300 enzymes, making it necessary for a wide variety of functions in our bodies. Fortunately, because it is found in many plant foods, deficiency is rare.

Potassium

The electrolyte potassium is abundant in the human body and has a critical relationship with sodium. Maintaining potassium inside and sodium outside cells is essential to both nerve and muscle function. Many health conditions have been linked to the high-sodium/low-potassium content of the Western diet. The best dietary sources of potassium are vegetables and fruit.

Sodium

The electrolyte sodium is one of the most misunderstood nutrients. It is critical to survival and has an important relationship with potassium. While hunter-gatherers consumed 1,000mg or less per day, a typical modern diet often exceeds 3,000mg and is linked to almost all chronic inflammatory conditions including hypertension, heart disease, cancer and autoimmunity.

Zinc

The mineral zinc serves a variety of functions in the body. The most well-known is its critical role in maintaining the health of our immune systems. Zinc deficiency is characterized by frequent illness. It is very difficult to get sufficient zinc purely from plant sources, especially since phytates in some plant foods prevent zinc absorption.

Folate

The fascinating thing about folate is that you likely won’t find it at the supplement store. Instead, you’ll find folic acid, which was invented in the 1940s; folic acid doesn’t exist in nature. Worse, folic acid has been associated with issues in pregnancy. To get real folate, eat your leafy greens, avocados, and organ meats.

Vitamin A

Vitamin A, or retinoic acid, is most well-known for its key role in maintaining healthy vision, but it also plays a critical role in gene expression. It is found in orange and yellow plants such as carrots. Vitamin A deficiency is rare in the first world and especially if you are consuming a Paleo Diet high in fruits and vegetables.

B Vitamins

There are several B vitamins that play numerous roles in the body, particularly related to energy. It’s important to know that vitamin B12 can’t be found in plants, and plant sources of B6 often aren’t bioavailable. Both are critical to preventing a build-up of homocysteine which has a higher correlation with heart disease than cholesterol.

Vitamin C

Vitamin C is a powerful antioxidant that is essential to survival. Deficiency is characterized by conditions like scurvy. However, much of the research touting it as a wonder pill for immune health and longevity has been debunked.

Vitamin D

Despite the name, vitamin D isn’t a vitamin. It’s a hormone that’s produced in our skin through sun exposure. In modern times, living indoors and using sunscreen have prevented us from producing enough vitamin D naturally. This is one of the few nutrients we recommend supplementing.

Vitamin E

Vitamin E is one of the few fat-soluble vitamins. It functions primarily as an antioxidant, and is essential at appropriate levels. However, since it is fat-soluble, our bodies cannot excrete any excess vitamin E (which is generally only possible with supplementation). Overconsumption has been associated with increased mortality rates. Our best dietary sources are seeds, nuts and olive oil.

Vitamin K/Menaquinones

Vitamin K represents a group of fat-soluble vitamins that promote clotting of the blood by increasing the synthesis of prothrombin in the liver. However, recent research suggests the potential health benefits of vitamin K go beyond its role as a trigger for hepatic coagulation factors.

Other Micronutrients

While there is a long list of known essential vitamins and minerals, the list of nutrients we still don’t understand is significantly larger. There are many beneficial nutrients (some phytochemicals) and harmful anti-nutrients such as lectins and saponins. Therefore, supplementing a nutrient-poor diet with a multivitamin continues to prove to have no health benefits, or to potentially be harmful.

The Paleo Diet October 2020 Digest - Protein

October’s theme was centered around protein. We talk about the health risks of overconsuming protein and how to get enough protein from plant foods. We also discuss the in’s and outs of eggs.

By The Paleo Diet® Team

Nell’s Corner: Three Protein Myths You Might Still Believe

We know we need protein, but things get confusing once we address how much we need and where we should be sourcing this important component of our diet. Read more for answers to common myths about protein.

By Nell Stephenson

Battle of the Proteins: Comparing Plant and Animal Sources

Is the quality of plant protein comparable to animal protein? By looking at protein sources’ amino acid profile and bioavailability we can determine that animal proteins provide significantly better nutrition than other sources.

By Mark J. Smith, Ph.D.

Protein, Fasting, and the mTOR Pathway

Over-eating, especially of protein, activates the mTOR pathway which some researchers associate with increased cancer risk and shortened lifespan. Balancing macronutrients, like protein, can be challenging, but by looking at our hunter-gatherer ancestors lifestyles we can see that fasting may be one way to help keep mTOR in check.

By David Whiteside

The Best Plant-Based Paleo Proteins

Interested in eating both vegetarian and Paleo? Here’s everything you need to know about proteins sourced from plants.

By Elisabeth Kwak

The Paleo Diet October 2020 Digest - Protein

October’s theme was centered around protein. We talk about the health risks of overconsuming protein and how to get enough protein from plant foods. We also discuss the in’s and outs of eggs.

By The Paleo Diet® Team

Battle of the Proteins: Comparing Plant and Animal Sources

By Mark J. Smith, Ph.D.

The Best Plant-Based Paleo Proteins

Interested in eating both vegetarian and Paleo? Here’s everything you need to know about proteins sourced from plants.

By Elisabeth Kwak

The research of Dr. Douglas London on one of the last remaining indigenous hunter-gatherer societies on Earth, part 2

In this follow-up interview, Dr. London discusses his upcoming research and dives deeper into the Kawymeno diet.

By Trevor Connor

Healthy Aging: Study shows high-carbohydrate diets promote dementia

Take a deep dive into research showing how eating a diet high in sugar can contribute to the onset of dementia and how a Paleo Diet can be protective

By David Whiteside

Eat Saint Louis Style Pork Ribs, and Reduce your Risk for Heart Disease, Osteoporosis and Other Chronic Diseases

St. Louis style pork ribs come from the healthiest part of the pig. Dr. Cordain of The Paleo Diet explains why their high menaquinone content may help your health in today's entry.

By Loren Cordain, Ph.D.

Reversing Nutritional Deficiencies by Eliminating Entire Food Groups

Are you hurting your health my eliminating entire food groups? But wait, haven't you been conditioned to do so from the beginning of time. Think again.

By Christopher Clark

Eliminating Non-Paleo Foods Improves Nutrient Density

Learn how eliminating non-paleo foods can help improve your nutrient density. Browse The Paleo Diet® blog for paleo diet news, paleo recipes & more!

By Loren Cordain, Ph.D.

Five Practical Tips for Getting Your B Vitamins

Here, we explain how you can get plenty of B vitamins while following a Paleo lifestyle. Browse our blog for Paleo recipes, news, and more!

By Christopher Clark

Pomegranate: Perhaps, Paleo’s Healthiest Fruit

Learn how the pomegranate is paleo's healthiest fruit. Browse The Paleo Diet® blog for the latest paleo diet news, paleo recipes, meal plans & more!

By Loren Cordain, Ph.D.

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Key Nutrients

The Paleo Diet October 2020 Digest - Protein

Nell’s Corner: Three Protein Myths You Might Still Believe

Battle of the Proteins: Comparing Plant and Animal Sources

Protein, Fasting, and the mTOR Pathway

The Best Plant-Based Paleo Proteins

The Paleo Diet October 2020 Digest - Protein

Battle of the Proteins: Comparing Plant and Animal Sources

The Best Plant-Based Paleo Proteins

The research of Dr. Douglas London on one of the last remaining indigenous hunter-gatherer societies on Earth, part 2

Healthy Aging: Study shows high-carbohydrate diets promote dementia

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Eliminating Non-Paleo Foods Improves Nutrient Density

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