Re-evaluating Dietary Milk Recommendations | The Paleo Diet®
noun_Search_345985 Created with Sketch.
noun_Search_345985 Created with Sketch.

The latest from The Paleo Diet®, just for you.

Hot topics, new recipes, and science

Re-evaluating Dietary Milk Recommendations

By The Paleo Diet Team
August 7, 2014
Re-evaluating Dietary Milk Recommendations image

Dear Professor Cordain,

In regards the review paper of which you were co-author: "The impact of cow’s milk-mediated mTORC1-signaling in the initiation and progression of prostate cancer," could you please inform me whether you are aware of any country’s medical community who has responded to your conclusive statement that: "…the medical community urgently needs to re-evaluate dietary milk recommendations."

This has not occurred thus far in my country of Australia.

Please excuse me for further taxing your valuable time, but could you also inform me of the details leading to the changing of the designation of the ‘m’ in the mTORC acronym from ‘mammalian’ to ‘mechanistic’, as it appears in your co-author Bodo Melnik’s 2013 paper: "Milk is not just food but most likely a genetic transfection system activating mTORC1 signaling for postnatal growth."

Many thanks in anticipation.
Kind regards,

Dr. Ross Partington

Bodo Melnik's Response:

Dear Dr. Partington,

Mammalian target of rapamycin (mTOR) has been renamed in an mTOR consensus conference to mechanistic target of rapamycin. The official nomenclature according to OMIM.org is now:

601231 MECHANISTIC TARGET OF RAPAMYCIN; MTOR

Alternative titles; symbols MAMMALIAN TARGET OF RAPAMYCIN FKBP12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1; FRAP1 FK506-BINDING PROTEIN 12-RAPAMYCIN COMPLEX-ASSOCIATED PROTEIN 1 FRAP FRAP2 RAFT1

The mTOR protein or function has not changed also there are various synonyms, a matter of history in molecular biology.

Best regards,

Bodo C. Melnik, Ph.D
Department of Dermatology
Environmental Medicine and Health Theory
University of Osnabrück, Sedanstrasse
Germany

Even More Articles For You

Fighting Cancer, Autism, and Neurodegenerative Diseases One Molecule at a Time
When your mother told you to eat your vegetables, she was right. Sulforaphane helps protect the brain and is found in many vegetables eaten on a Paleo Diet.
By Casey Thaler
Coconut Oil: The Ultimate Fat, or Completely Terrible for You?
Coconut is one of the most popular Paleo staples, but there is some confusion about its health benefits and risks. Learn about the evidence from the experts at The Paleo Diet!
By Casey Thaler
Kefir Consumption Ill Founded at Best
Learn more about kefir consumption & its benefits. Visit The Paleo Diet® website for easy Paleo diet recipes, Paleo diet menus & tips today!
By Loren Cordain, Ph.D.
Paleo Leadership
 
Trevor Connor
Trevor Connor

Dr. Loren Cordain’s final graduate student, Trevor Connor, M.S., brings more than a decade of nutrition and physiology expertise to spearhead the new Paleo Diet team.

Mark J Smith
Dr. Mark Smith

One of the original members of the Paleo movement, Mark J. Smith, Ph.D., has spent nearly 30 years advocating for the benefits of Paleo nutrition.

Nell Stephenson
Nell Stephenson

Ironman athlete, mom, author, and nutrition blogger Nell Stephenson has been an influential member of the Paleo movement for over a decade.

Loren Cordain
Dr. Loren Cordain

As a professor at Colorado State University, Dr. Loren Cordain developed The Paleo Diet® through decades of research and collaboration with fellow scientists around the world.