Alternatives To Gluconeogenesis For Rebuilding Post Workout Glycogen Levels

Gluconeogenesis | The Paleo Diet

Dr. Cordain,

Hello there. I am sure you receive a generous amount of email, so I will not waste time with small talk and hope you actually get this email. Long story short: I earned my undergraduate in nutrition from University Nevada Reno in 2003. I left the world of academia with my general understanding of nutrition and felt ready to conquer the world of unhealthy eating ha! I have been doing a bit of research on the paleo diet as well as some others. I have been attempting to try out the paleo diet on myself as a sort of experiment. I had actually stopped eating grains for the most part about 5yrs ago, so it hasn’t been that difficult. What I am ultimately wondering is whether gluconeogenesis via the use of protein aka amino acids and efficient way to rebuild muscle glycogen (well liver glycogen and then to muscles). I just don’t want to be turning my wheels in the gym. It seems like maybe my body will adapt, but I have felt so fatigued at gym. I bonk within the 1st 15 20 min. Maybe I should add more carbs but it is difficult to know which carbohydrates I can eat. I’m not going to lie, I kind of want to just go eat a bowl of dairy filled ice cream and quickly revamp my glycogen. I am sure you are busy, but any help or resources would be greatly appreciated.



Dr. Cordain’s Response:


Building glucose and then glycogen via gluconeogenesis is a very inefficient pathway. A better strategy is to obtain your carb stores as Joe Friel and I have outlined in our newly revised 2012, The Paleo Diet for Athletes. This book describes how Paleo foods such as sweet potatoes, yams, bananas, fresh fruit, fruit juices and dried fruit are both Paleo friendly and help to restore muscle glycogen. Additionally, we describe how to top off muscle glycogen before, during and after workouts and competition. Finally, by eliminating grains and refined carbs, you will force your body’s metabolic machinery to rely more upon stored intramuscular triglyceride (IMT) which will increase beta oxidation of IMT, which is a highly labile source of ATP during exercise. Higher muscle concentrations of IMT “spare” muscle glycogen and actually allow you additional time before muscle glycogen stores are depleted causing you to bonk. Many high level endurance athletes have successfully employed “Paleo” to improve performance.


Loren Cordain, Ph.D., Professor Emeritus

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About the Author:

Loren Cordain, PhD, Professor Emeritus Dr. Loren Cordain is Professor Emeritus of the Department of Health and Exercise Science at Colorado State University in Fort Collins, Colorado. His research emphasis over the past 20 years has focused upon the evolutionary and anthropological basis for diet, health and well being in modern humans. Dr. Cordain’s scientific publications have examined the nutritional characteristics of worldwide hunter-gatherer diets as well as the nutrient composition of wild plant and animal foods consumed by foraging humans. He is the world’s leading expert on Paleolithic diets and has lectured extensively on the Paleolithic nutrition worldwide. Dr. Cordain is the author of six popular bestselling books including The Real Paleo Diet Cookbook, The Paleo Diet, The Paleo Answer, and The Paleo Diet Cookbook, summarizing his research findings.

6 Comments on "Alternatives To Gluconeogenesis For Rebuilding Post Workout Glycogen Levels"

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