Tag Archives: testimonial

Lupus | The Paleo Diet

Hello Dr. Cordain,

I hope this finds you in good health. Prior to 2009 I lost 100lbs and began my career as a fitness professional teaching cycling classes and helping others reach their weight loss goals. 2009 I was diagnosed with Lupus and went into total kidney failure. I spent 8 weeks living a Georgetown University Hospital in Washington, DC and some how made a miraculous recovery.

Of course I was put on lots of medication and had to go through a sort of chemo for about a year afterwards. Now I find myself struggling to lose the weight I gained back after being on prednisone for years. Now I’m battling moments of depression and exhaustion despite still teaching my cycling classes and trying to eat “healthy.” Also, I’m still taking prednisone but my dose is only 5mg now.

I’ve finally been cleared by my kidney doctor to start taking in more protein and I immediately thought of Paleo. Can you give me a little more insight as to how Paleo may help me? Nobody around me eats this way, including the people I live with, so I would be doing this all alone. But, in my gut, I believe it might be the answer I’ve been looking for. Hope to hear from you soon. Take care.

Anonymous

Dr. Cordain’s Response:

First, let me say that my heart goes out to you for the health problems you have been experiencing associated with your diagnosis of systemic lupus erythematosus (SLE). I am not a clinical practitioner, but rather a University Researcher studying diet and autoimmunity. Accordingly, I suggest that you consult a variety of health care professionals who are familiar with SLE, autoimmunity and The Paleo Diet. Competent health care personnel can work with you individually and over time to regularly monitor your signs and symptoms of SLE, your blood chemistry and your overall health if you decide to adopt The Paleo Diet.

The Paleo Diet may help to reduce or even cause remission of autoimmune disease symptoms in certain autoimmune conditions. Our international research group believes that contemporary Paleo diets may be therapeutic for some autoimmune disease patients for a number of reasons. First, this nutritional program eliminates a number of foods which may increase intestinal permeability. Evidence from our laboratory (1) as well as more recent data (2, 3) suggests a “leaky gut” may represent an important environmental/dietary factor which triggers autoimmune disease in genetically susceptible patients.

As with The Paleo Diet for all people, I suggest autoimmune subjects reduce or eliminate cereal grains, particularly gluten containing grains (wheat, rye and barley). Cereal grains contain a number of compounds which may increase intestinal permeability including gliadin (a storage protein found in gluten containing grains), lectins (particularly a lectin called wheat germ agglutinin [WGA] found in wheat, and thaumatin like proteins, as well as other compounds.

Over the past two decades, SLE has frequently been reported to present simultaneously with celiac disease (4-6), an autoimmune intestinal disease caused in genetically predisposed patients by consumption of gluten containing grains. Both SLE and celiac patients share the genetic markers (HLA B8 and DR3) which increase disease susceptibility. Further a recent study indicated that 7 of 24 SLE patients exhibited anti-gliadin antibodies, the same antibodies to gluten containing grains found in celiac patients. A number of case reports have shown that gluten free diets had beneficial and favorable effects in SLE patients (6, 7). Accordingly, the preliminary evidence suggest that SLE patients should adopt gluten free diets.

Check out my former graduate student, good friend and colleague, Robb Wolf’s website and read about an SLE patient who beat the disease with Paleo. There is absolutely no risk to gluten free diets like The Paleo Diet, and the potential for improved health is high (8-15).

Other foods which are not on The Paleo Diet menu are dairy products, legumes, processed foods, refined sugars and vegetable oils. All of these items may adversely affect intestinal function or interact with the immune system in a manner that may promote allergy or autoimmunity. For details about these and other dietary elements that compromise intestinal function see my latest book, The Paleo Answer.

Finally, autoimmune patients may also want to read Egg Whites and Autoimmune Disease which suggests eggs and nightshades sometimes interact with the immune system to promote or aggravate allergy and autoimmunity.

Cordially,

Loren Cordain, Ph.D., Professor

References

1. Cordain L, Toohey L, Smith MJ, Hickey MS. Modulation of immune function by dietary lectins in rheumatoid arthritis. British Journal of Nutrition, 2000, 83:207-217.

2. Fasano A. Leaky gut and autoimmune diseases. Clin Rev Allergy Immunol. 2012 Feb;42(1):71-8.

3. Fasano A. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiol Rev. 2011 Jan;91(1):151-75

4. Mirza N, Bonilla E, Phillips PE. Celiac disease in a patient with systemic lupus erythematosus: a case report and review of literature. Clin Rheumatol. 2007 May;26(5):827-8

5. Freeman HJ. Adult celiac disease followed by onset of systemic lupus erythematosus. J Clin Gastroenterol. 2008 Mar;42(3):252-5

6. Hrycek A, Siekiera U. Coeliac disease in systemic lupus erythematosus: a case report.
Rheumatol Int. 2008 Mar;28(5):491-3.

7. Zitouni M, Daoud W, Kallel M, Makni S. Systemic lupus erythematosus with celiac disease: a report of five cases. Joint Bone Spine. 2004 Jul;71(4):344-6

8. Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC, Jr., Sebastian A: Metabolic and physiologic improvements from consuming a paleolithic, hunter-gatherer type diet. Eur J Clin Nutr 2009.

9. Jönsson T, Granfeldt Y, Ahrén B, Branell UC, Pålsson G, Hansson A, Söderström M, Lindeberg S. Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study. Cardiovasc Diabetol. 2009;8:35

10. Jonsson T, Ahren B, Pacini G, Sundler F, Wierup N, Steen S, Sjoberg T, Ugander M, Frostegard J, Goransson Lindeberg S: A Paleolithic diet confers higher insulin sensitivity, lower C-reactive protein and lower blood pressure than a cereal-based diet in domestic pigs. Nutr Metab (Lond) 2006, 3:39.

11. Jonsson T, Granfeldt Y, Erlanson-Albertsson C, Ahren B, Lindeberg S. A Paleolithic diet is more satiating per calorie than a Mediterranean-like diet in individuals with ischemic heart disease. Nutr Metab (Lond). 2010 Nov 30;7(1):85

12. Lindeberg S, Jonsson T, Granfeldt Y, Borgstrand E, Soffman J, Sjostrom K, Ahren B: A Palaeolithic diet improves glucose tolerance more than a Mediterranean-like diet in individuals with ischaemic heart disease. Diabetologia 2007, 50(9):1795-1807.

13. O’Dea K: Marked improvement in carbohydrate and lipid metabolism in diabetic Australian aborigines after temporary reversion to traditional lifestyle. Diabetes 1984, 33(6):596-603.

14. Osterdahl M, Kocturk T, Koochek A, Wandell PE: Effects of a short-term intervention with a paleolithic diet in healthy volunteers. Eur J Clin Nutr 2008, 62(5):682-685.

15. Ryberg M, Sandberg S, Mellberg C, Stegle O, Lindahl B, Larsson C, Hauksson J, Olsson T. A Palaeolithic-type diet causes strong tissue-specific effects on ectopic fat deposition in obese postmenopausal women. J Intern Med. 2013 Jul;274(1):67-76.

Changed My Life with The Paleo Diet

Hi Dr. Cordain,

Trust you are well. I would like to take this opportunity to share my success story with you…

Paleo has seriously changed my life forever. I started my new lifestyle 19/08/2012. Since then, I have lost 50 kg without the assistance of any medical intervention.

I learned about Paleo via Fat-Burning Man – Abel James’s Podcast which I stumbled upon while searching for a way to improve my life. After only listening to one podcast, I was convinced that Paleo is for me and that it will change my life, which, fortunately for me, it did.

My life before Paleo was seriously miserable. It was almost like as if I was collecting illnesses/conditions, Gastro Esophageal Reflux, Hernia, Cellulitis, High Blood Pressure, Depression, Sleep Apnea, Insomnia, Migraine and Acne just to mention a few.

Moving around, doing physical tasks really became very difficult. Socially, I did not gel anymore. Buying clothes really become a huge problem, as I was unable to find suitable clothes that I like and in my size. Suicide almost became a daily thought…

Today, I am a completely different person. My social circle has grown from just a handful of friends to many. My cholesterol is now normal and all of my past daily illnesses/conditions are also gone. I have gone from size XXXL to M shirts and from a 44” waist to 30” waist.

My mindset about health and food has changed completely. I am a Software Engineer/Developer by trade, but am considering a new profession and adventure as a Nutritionist/Dietitian.

I am advocating Paleo on a daily basis, motivating people to follow my lead and Paleo. Paleo is not a complex lifestyle and really easy to follow.

Thank you for letting me share my story! I hope that it will motivate and encourage other people.

My photos as proof, as photos do not lie.

Paleo is the best…!!!

Regards,

Adriaan

Dr. Cordain’s Response:

Adriann,

Congratulations upon your wonderful success story. I know that it will motivate others to follow as well. Keep up the good work and thank you for sharing it with me.

Loren Cordain, Ph.D., Professor Emeritus

Cured My Esophagitis | The Paleo Diet

Dear Dr. Cordain,

I’m just sending a quick testimony to thank you for The Paleo Diet. It cured my esophagitis, which I had for 6 months straight, in less than 3 weeks. It seemed miraculous. I can even eat citrus and marinara sauce and drink coffee, tea, and wine again with absolutely no problems whatsoever. I discovered Paleo through Chris Kresser’s website when researching my health problems online.

I had been a vegetarian since the age of 10 and ate at least 80% grains, dairy and legumes since then. I’m now 29 and until last month I couldn’t understand why at my age I kept developing illnesses (colitis, esophagitis, and IBS, plus I was sleeping 10 hours at a time and still feeling tired.) I thought that perhaps I was doomed due to bad genes because these things run in my family on both sides (family members with Barrett’s Esophagus, Colostomy bags, Acid Reflux), but now I’m already all better! I’m totally healthy, full of energy, and as an added bonus, I lost a few pounds and am as skinny as I was as a teen. It happened so fast too! I can hardly believe it.

Thank you very much! I’m so happy to be off of medicine and symptom free! It is a huge relief.

Sincerely,

Sarah
Dr. Cordain’s Response:

Hi Sarah,

Congratulations upon your health successes with Paleo! Success stories like yours really are what this idea is all about — helping people to enjoy a better quality of life. Hopefully, others with similar conditions can benefit from your anecdotal experience.

Regards,

Loren Cordain, Ph.D., Professor Emeritus

testimonial-the-paleo-diet

Hello Dr. Cordain,

I wanted to send you a note to connect and introduce myself.  Almost two years ago, I read your book, The Paleo Diet, and forever changed my life’s direction.

My culinary training is classical French with a twist of all that makes New American.  I ran a successful catering business in Atlanta for 7 years and in searching for a healthy way for my wife and I to eat, I read your book.  The smiles started from the first page when you gave tribute to S. Boyd Eaton. I catered a family BBQ for Boyd and Daphne a few years back! (They served corn by the way).

Reading on a flight back from London, I  found myself not able to put the book down, and not able to find flaw in anything you wrote. I said to myself this is it!  I proceeded to go in 100% and had amazing results.  Losing 35 lbs in 2.5 months, 10% BFI loss, increased muscle mass, just doesn’t happen when you are a chef.  My energy, and drive skyrocketed as I felt half my age.

I knew this was the direction not only for me, and my wife but my customers. I developed my product Pre-Made Paleo and never contracted another non-Paleo meal since.  Our meals are developed with classic technique using Paleo ingredients. My vision for my company is to change the way people eat. We now have a production kitchen focused completely on Pre-Made Paleo Meals and products that ship to all 50 states!

Thank you so much for your research, and shared knowledge.

All the best,

Chef Richard Bradford

Dr. Cordain’s Response:

Hi Richard,

Good to hear from you — congratulations upon your weight loss and health successes with the Paleo Diet.  I am also happy to know that I have such a well known culinary ally with the knowledge and abilities to bring the Paleo Diet to the cookery world.

Cordially,

Loren Cordain, Ph.D., Professor Emeritus

Affiliates and Credentials