Genetic Changes and Modern Diet Excerpt
Exercise, sleep, sun exposure and dietary needs of every living organism are genetically determined. This is why it is becoming increasingly recognized that the profound changes in diet and lifestyle that occurred in the last 10,000 years are too recent for the human genome to have adapted.
There certainly have been some genetic changes since the Agricultural Revolution that can affect certain dietary needs. These include an increase in the number of copies of the gene AMY1, which codes for salivary amylase (the enzyme responsible for starch digestion), various hemoglobinopathies, Adult Lactase Persistence – ALP (which affects about 25% of the human population), the polymorphism MTHFR 677CC27 (which affects folic acid status),mutations in the gene HFE, that may lead to hemochromatosis (iron overload) deficiency in the enzyme glucose-6-phosphate dehydrogenase (which could make fava beans potentially toxic) and other polymorphisms.
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